Pancreatitis: Monitor for signs and symptoms of pancreatitis (such as severe abdominal pain that may radiate to the back, with or without vomiting). Discontinue sitagliptin if pancreatitis is suspected.
Renal Impairment: Dose adjustment may be necessary in patients with renal impairment. Regularly monitor kidney function.
Hypoglycemia: Be cautious of hypoglycemia, especially if used in combination with other antidiabetic medications such as sulfonylureas or insulin.
Allergic Reactions: Be aware of the potential for serious allergic reactions. Discontinue use and seek immediate medical attention if hypersensitivity reactions occur.
Drug Interactions: Inform your healthcare provider of all medications you are taking, as sitagliptin can interact with other drugs.