Precautions:

Regular monitoring of liver function tests is recommended before and during treatment
Caution in patients with a history of liver disease or heavy alcohol use
Patients should report any unexplained muscle pain, tenderness, or weakness, particularly if accompanied by malaise or fever

Drug Interactions:

Increased Risk of Myopathy/Rhabdomyolysis: When taken with drugs such as fibrates, niacin, or certain protease inhibitors
Increased Blood Levels of Atorvastatin: When taken with drugs such as cyclosporine, clarithromycin, or certain antifungals (e.g., itraconazole)
Grapefruit Juice: Can increase atorvastatin levels and should be consumed in moderation